Thursday 11 September 2008

Know how to drugs cure Alzhimers Diease?


Alzhimers

Although there is no strong evidence that any way of life change can avoid Alzhimers disease, studies recommend that certain behaviors may help protect against mental decline. In particular, medications and lifestyle choices that keep the heart may be of specific importance. A variety of preventive drugs are under research, including antioxidant and anti-inflammatory therapies. How you suppose that the drug can be as healing for people with Alzhimers? But this factual reality! Believe it or not..Let’s start with first ways to prevent Alhimers Disease

1) Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) as Prevention

In 2004, the National Institutes of Health (NIH) halted a large clinical trial that was investigating the use of anti-inflammatory drugs in preventing Alzhimers disease. While previous data had confirmed that NSAIDs were not helpful in treating AD (refer to Alzhimers Disease), research continued to explore these drugs' potential preventive benefits.

The Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT) investigated whether long-term use of naproxen (Aleve) or celecoxib (Celebrex) could decrease the risk of developing AD. The NIH suspended this trial due to evidence that the NSAID naproxen was associated with increased incidence of cardiovascular and cerebrovascular events among participants. (The evidence is not uniform; other research has not concerned naproxen as a cardiovascular risk.) No adverse effects appeared during this trial for the COX-2 inhibitor celecoxib. However, safety concerns about this drug had been raised in other trials. Investigators did not consider that celecoxib's potential benefits outweighed its risks.

2) Heart-Protective Medications and Behaviors

The same lifestyle and medical choices that reduce risk factors for heart disease and diabetes may be important for reducing the risk for Alzheimer's disease. The following are some heart-protective medications that may also protect the brain.
Blood Pressure Drugs. Because high blood pressure is associated with increased risk of Alzheimer’s, researchers have been studying whether blood pressure medication can reduce this risk. In a 2006 study of patients who took high blood pressure drugs, researchers found that potassium-sparing diuretics reduced the risk of developing Alzheimer’s by 70%. Beta-blockers and certain calcium channel blockers also helped to a lesser extent. ACE inhibitors appeared to offer no protection.
Statins. Statins are common drugs used to lower cholesterol levels. In past years, a number of studies reported a significantly lower risk for Alzheimer's disease in patients who took statins. However, newer studies have failed to prove that statins can help prevent Alzheimer's disease. In these recent studies, large numbers of elderly people had their dementia evaluated at baseline and then monitored over several years. The results indicated that statin use did not predict onset of AD. In the meantime, the NIH is conducting a clinical trial to investigate whether simvastatin can slow the progression of Alzhimers Disease.
Male and Female Hormone Replacement Therapies

Hormone Replacement Therapy. Hormone replacement therapy (HRT) has been studied for years for health effects after menopause, including its effect on mental decline. A number of studies, including a major 2003 analysis, have found no differences in mental performance and no protection from Alzhimers disease in women taking HRT compared to non-users. The 2003 trial, called the Women's Health Initiative Memory Study (WHIMS), enrolled 4,500 women over 65 years of age. The WHIMS study showed that older postmenopausal women who took combination HRT (estrogen plus progestin) had twice the risk of developing dementia than similarly aged women who received placebo pills. In addition to increasing the risk for dementia, (including Alzhimers disease), combination HRT failed to prevent the development of mild cognitive impairment. Based on these results, the researchers from the National Institute on Aging (NIA) recommended against prescribing combination hormone therapy to older women for maintaining or improving cognitive function. The NIA continued to research whether estrogens-only therapy could prevent or delay the onset of Alzheimer's disease. Results released in 2004 indicated that women ages 65 years and older who took estrogens-only HRT had a slightly increased risk of developing dementia.
Testosterone. Some testosterone converts to estrogen, which may be why older men appear to have a lower risk for Alzheimer's disease than older women. Animal studies have suggested that testosterone may help reduce levels of beta amyloid. There is also some evidence that low testosterone levels may be a particular risk factor in men with the APOE4 gene. Some experts believe that giving testosterone to elderly men and combinations of testosterone and estrogen to older women may prove to be protective. Side effects of testosterone in women include increased body hair, acne, fluid retention, anxiety, and depression. Long term benefits or serious adverse effects are unknown.

DHEA. Dehydroepiandrosterone (DHEA) is a male-like hormone in the body that declines with age. Some evidence suggests that it may help reduce mental decline in older women, but not in older men. Studies are under way. The hormone may, however, reduce HDL (the so-called good cholesterol) when taken in higher doses and its effect on cancer-cell growth is unknown. Some evidence indicates that high levels may increase cancer risk. In any case, DHEA is not regulated and brands vary widely in their content.

We will be continue in our next lesson that include Dietary Factors and other Health Behaviours......


P/S : I want to ask for forgiveness meant for my editorial before since some readers don’t empathize about what article for. So, I wish that you will get pleasure from this piece of writing.Thanks


Alzhimers


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Tuesday 9 September 2008

Preventing Alzhimers disease!


Alzhimers

When one bay the after years of one’s life, systems will apathetic bottom ward and basic will weaken. This is the time back you will not be able to do the things that you acclimated to do adore or if you were still able to do it, you would not be able to do it with the aforementioned acceleration and backbone as you acclimated to before.

That is the sad actuality about aging. Things will apathetic bottom ward and eventually, little by little, disappear.

But that is not consistently the case. For some people, the crumbling actions can acceleration up abnormally in the breadth of the brain.

This is what scientists alarm Alzhimers.

It is a degenerative and accelerating ache that targets the brain, decidedly the areas that accord with acquirements and memory. Although it generally affects bodies over the age of 80, there are some who are diagnosed with the botheration as aboriginal as their 40s and 50s. There are additionally attenuate cases back Alzheimer’s attacks at backward 20s.

Alzhimers Ache is characterized by a accelerating amnesiac accident and disability to focus absorption on one thing. Bodies with this ache will balloon their names, their addresses and will cease to admit their husbands, accouterments and bodies who are abutting to them.

When it is on its after stages, accent problems may additionally appear because of the disability of the being to anamnesis words that are adapted for what they are activity to say. The ache may additionally after-effects to behavioural changes because of accelerating anamnesis loss. There are some patients who don’t bethink how to go about their familiar functions such as eating, sleeping or abrasion their teeth. Some may alike balloon how to breathe.

This is the acumen why best old bodies alarming this disease. It can absolutely be debilitating, annexation you of your activity and generally times your admired one.
Although annihilation has been accurate yet, some studies appearance that accomplishing brainy tasks can absolutely apathetic bottom ward the progression of the disease. For instance, patients who adulation to acknowledgment puzzles and comedy brainy amateur like chess are slower in their progression compared to added patients with the aforementioned amount and case of Alzhimers. Because of this, some scientists accept that Alzhimers can be prevented through the use of the brainy process.

Below are some means to anticipate Alzhimers from clearing in.

Learn article new
Old age is not acumen to stop acquirements new things. You can apprentice an array of things, dancing, cooking, singing, a new language, crafts, the arts. There are so abounding things to accept from. Don the things that you accept not done before, things that you never thought, you’ll be doing. Your age should not be albatross to the things that you appetite to do.

In accession to adorning your life, acquirements article new affords a beginning claiming for your brains. This way, your brainy processes will be acclimated already again. This keeps the academician beef in appearance and sharp.
Play apperception games

This is not to say that you should be artful and plotting, active the baiter for the associates of your family. Apperception amateur actuality accredit to the tamer kind, crossword puzzles, sudoku. These are means to acuminate those brainy abilities and memory. This additionally allows you to convenience or be accustomed with words and things already again, abbreviation the adventitious of you apathy them.
My suggestion, just always give your full attention in all things. No matter that it is big things or small and don’t eat crap foods.

Alzhimers


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Sunday 7 September 2008

Actions for people through Alzhimers


ALZHIMERS

Alzhimers is one disease that people horror to be diagnosed with. Who can blame them?

It is one of the most debilitating diseases known to man and it affects not only one area or one system but all. Of course, since it is a progressive disease, effects on the various systems of the body does not happen at one time.

As the disease progress, the effects become wide-range.

Alzhimers disease is perhaps the best-known disease under Dementia, a disorder that affects the mental processes. It is characterized by the progressive loss of memory that may lead to inattentions and inability to focus at a job, language problems and behavioural changes.

Patients with Alzhimers disease for instance may initially find themselves at a loss for words or unable to remember some bits of facts that happened the day before. But as the days progress, they will find themselves starting to forget important things like their addresses, their age and sometimes even their names.

Patients who are in the later stages of Alzhimers will start to forget how to do routinely things like brushing their teeth, taking a bath or using their utensils. Some may not speak altogether because they will regularly forget the words that they should be using or saying. Some will also behave differently, brought on by the frustration of not being able to do the things that they used to do. Often times, patients at the later stages will become dependents, acting like children who do not know what to do with themselves.

Although there are medicines that can slow down the progress of the disease especially if discovered early on, there is no solution to the problem. Once it settles into the system, it would be there for life and there is no chance of it ever disappearing.
Like medicines, there are activities that according to scientists can slow down the progression. Below are just some of them:

1) Read

Something as simple as reading the newspaper each day and keeping your mind informed with the latest news is already something that can avoid the disease from settling in. Just make it a point to use your brain. Be an analytical reader and elevate questions and do not just absorb the texts and then forget about it. Being an active reader and allowing your imagination free control will go a long way for exercising the brain. In fact, studies have shown that people who are in love with to read are less likely to be diagnosed with Alzhimers.

2) Answer puzzles

Another mental exercise that people with Alzhimers do to help slow down the process is to answer puzzles such as word hunts, cross words and even Sudoku. The more that you use your brain, the better will be your prognosis. Answering word games will also make sure that you rehearsal words and increase your vocabulary, making it less likely for you to forget words and language.

3) Attend classes

Being old does not mean that you cannot learn. Patients with Alzhimers should make it a point to learn something new. This will exercise their brains. A creative task such as arts and crafts is another way to tap into the brain’s resources without tiring them out. Learning a new thing also gives people with Alzhimers the sense of purpose that they have lost since they were diagnosed with the disease.

Beside that, we need to put more consideration on them because there are no treat aside from with our love and concerned.

For reader’s information:-

Alzhimers disease is not just a disease of the elderly. Early-onset Alzhimers accounts for up to 10% of Alzhimers cases and may strike people in their 30's, 40's or 50's. Although the person with the early-onset form of Alzhimers will experience similar symptoms as do all people with the disease, they may have to deal with some unique issues.


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